By O.P. Agarwal, M.D., F.I.C.A. 

Angiology, Vol 36, Number 8, August 1985 

Presented at the 31st Annual Meeting, American College of Angiology and

26th Annual Meeting,International College of Angiology, November 5, 1984.

Aloe Vera Australia Products. Please click here… Aloe Vera Australia

 

Abstract  

Five thousand patients of atheromatous heart disease, presented as angina pectoris, were  studied over a period of five years. After adding the “Husk of Isabg ol” and “Aloe vera” (an  indigenous plant known as ghee-guar-ka-paththa) to the diet, a marked reduction in total  serum cholesterol, serum triglycerides, fasting and post parandial blood sugar level in  diabetic patients, total lipids and also increase in HDL were noted. Simultaneously the  clinical profile of these patients showed reduction in the frequency of anginal attacks and  gradually, the drugs, like verapamil, nifedipine, beta-blockers and nitrates, were tapered.  The patients, most benefitted, were diabetics (without adding any antidiabetic drug). The  exact mechanism of the action of the above two substances is not known, but it appears, that  probably they act by their high fibre contents. Both these substances need further evaluation.  The most interesting aspect of the study was that no untoward side effect was noted and all  the five thousand patients are surviving till date.

Many people also advocate drinking the juice of the aloe vera plant, saying that it can relieve heartburn, alleviate IBS, lower your blood sugar, and a broad range of other claims. (1)

Aloe Vera Australia Products. Please click here… Aloe Vera Australia

 

Introduction  

Incidence of atheromatous heart disease is increasing day by day. The factors commonly  responsible for atherosclerotic heart disease are diabetes mellitus, hypertension, smoking,  family tendency in the form of hyperlipidemias, gout, excessive intake of saturated fatty  acids, obesity, lack of exercise, etc. 

 

Heart Disease

Not getting enough physical activity can lead to heart disease—even for people who have no other risk factors. It can also increase the likelihood of developing other heart disease risk factors, including obesity, high blood pressure, high blood cholesterol, and type 2 diabetes. (2)

Promotes heart health: Drinking aloe vera juice could internally help you to improve blood circulation in the body. Aloe vera is known to decrease total fat levels in patients with high cholesterol. This further helps in reducing fatty deposits and blood clots in the arteries of the heart. (3)

Organic Aloe vera Juice 6 Pack

Aloe Vera Australia. Please click here… Aloe Vera Juice

 

Diabetes

A new study highlights the anti-diabetic effects of aloe vera. The plant, which originates from Africa, has been found to reduce blood sugar levels, which can be helpful for patients suffering from type 2 diabetes.

Diabetes patients could have a reason to take a regular dose of aloe vera, as this succulent plant has been found to keep blood sugar levels in check.

For 6,000 years, aloe or aloe vera plants, which are native to Africa and certain Indian Ocean islands, have been used in phytotherapy, dermatology and cosmetics in the form of gels and creams.

American researchers published this week a review of nine studies exploring the plant’s benefits for type 2 diabetes patients in the “Journal of Alternative and Complementary Medicine.”

According to the various sets of data, taking aloe vera as an oral supplement can significantly reduce the level of glucose in the blood (46.6 mg/dl), as well as reducing HbA1c (1.05%), or glycated hemoglobin, which indicates the average blood glucose level over the previous three months.

Regularly taking aloe vera stimulates the secretion of insulin, which is particularly useful for people suffering from diabetes. Patients with blood sugar levels of 200mg/dl benefitted the most from the effects of aloe vera, the researchers found.

Diabetes is diagnosed when a patient’s fasting blood sugar level is greater than or equal to 130 mg/dl, or when it rises to 200 mg/dl or more one to two hours after a meal. (1)

4 Litre Organic Aloe Juice (Micropulp)

Aloe Vera Australia. Please click here… Aloe Vera Juice

 

Hypertension

Researchers found that consuming up to two ounces of aloe vera juice ($16.5, Aloe Vera Australia) per day could remedy high blood pressure (2)

1 Litre Organic Aloe Juice (Micropulp)

Aloe Vera Australia Products. Please click here… Aloe Vera Australia

 

For the first time, an Indian plant known as Aloe vera belonging to the Liliacee family along  with the Husk of Isabgol, was tried on five thousand patients who had proved ischaemic heart  disease due to atherosclerosis and the above two herbal medicines proved to be very effective  when mixed with wheat flour paste before preparing the bread. This plant; Aloe vera, is used

in Indian medicine as a tonic, purgative, aphrodisiac, antihelminthic, in various  opthalmological disorders, enlargement of spleen, various forms of hepatitis, vomiting, fever  due to bronchitis, erysipelas, skin disorders, asthma, leprosy, jaundice, strangury, as a  carminative, various musculoskeletal disorders, menstrual suppression and various other nonspecific disorders.

TABLE #1


 

Aloe Vera Australia Products. Please click here… Aloe Vera Australia

 

 

TABLE #2


Aloe Vera Australia Products. Please click here… Aloe Vera Australia

 

 

TABLE #3


 

 

Aloe Vera Australia Products. Please click here… Aloe Vera Australia

 

 

Table #4


 

Aloe Vera Australia Products. Please click here… Aloe Vera Australia

 

 

Table #5

 

Aloe Vera Australia Products. Please click here… Aloe Vera Australia

 

 

Table #6


Aloe Vera Australia Products. Please click here… Aloe Vera Australia

 

 

Table #7


Aloe Vera Australia Products. Please click here… Aloe Vera Australia

 

 

The plant has never been tried in the prevention of atherosclerotic heart disease. The other  substance, Husk of Isabgol, in Indian medicine is mainly used to increase the bulk of faeces  in constipation. This study is mainly based on its antiatherosclerotic properties.

 

Materials And Methods  

Five thousand patients were selected for the study ranging from 35-65 years of age. (Table  I) All patients had clear cut evidence of ischaemic heart disease in the form of unequivocal  ECG changes apart from effort angina. (Table II) All patients were subjected to serum  chemistry and were screened for fasting blood sugar, post parandial blood sugar (Table III),  total serum cholesterol (Table IV), serum triglycerides (Table V), total lipids (Table VI),  HDL cholesterol (Table VII), BUN & other investigations were normal.

Out of 5’000 patients, 3167 were diabetics; 2572 patients had a history of smoking 10 to 15  cigarettes per day, for about five years; 2151 patients had evidence of hypertension which  was not renal in origin. Out of these 2151 hypertensives, 1360 had mild hypertension and  791 patients had moderate hypertension. The patients, who had unstable angina, past history  of myocardial infarction, severe hypertension, severe diabetics & patients on insulin  therapy, history of left ventricular failure, gout, were not included in the study. Out of 1065  male non-diabetics, 912 had family history of hyperlipidemia and out of 768 female non diabetic patients, 454 patients were having family history of hyperlipidemia. All 5000  patients were instructed not to consume alcohol in any form during the study. Smoking was  also not allowed during study period.

All 5’000 patients were instructed to take 100 gms of fresh flesh gelatin of the plant Aloe  vera and 20 gms of Husk of Isabgol mixed with wheat flour to prepare the bread. These  breads were consumed at lunch and dinner. Apart from this, the strict dietary schedule and  the drugs, which these patients were already taking, in the form of beta blockers, verapamil,  nifedipine, isosorbide dinitrate, sulphonylureas, digoxin and diuretics and B-complex, were  asked to continue and report weekly. All these patients were assessed clinically and  biochemically.

Table #8


 

Aloe Vera Australia Products. Please click here… Aloe Vera Australia

 

 

TABLE #9


Aloe Vera Australia Products. Please click here… Aloe Vera Australia

 

 

TABLE #10


Aloe Vera Australia Products. Please click here… Aloe Vera Australia

 

 

TABLE #11

 

Aloe Vera Australia Products. Please click here… Aloe Vera Australia

 

 

TABLE #12


Aloe Vera Australia Products. Please click here… Aloe Vera Australia

 

 

TABLE #13


Aloe Vera Australia Products. Please click here… Aloe Vera Australia

 

 

TABLE #14


Aloe Vera Australia Products. Please click here… Aloe Vera Australia

 

 

Results 

Most of the patients started responding from second week after the therapy was instituted.  The improvement was noticed in the form of disappearance of angina pectoris and feeling of  well being. The ECG changes also started improving and from 3 months to one year all  patients, except 348, had normal tracing even after treadmill (Table VIII).

None of the patients suffered fresh myocardial infarction during the study. The lipid profile  also started improving after three months of institution of therapy (Table IX).

Out of 5000 patients, 4652 patients had their normal levels of serum cholesterol ranging  from 160 Mgm to 240 Mgm%, serum triglycerides from 50-90 Mgm% (Table X).

Total lipids from 500 Mgm to 800 Mgm% (Table XI), HDL cholesterol ranging from 50  Mgm to 75 Mgm% (Table XII).

Out of 3167 diabetic patients, the blood sugar values, fasting and post parendial, started  coming down to normal levels (Table XIII) except in 177 patients, and all the oral  hypoglycemic agents had to be withdrawn by the end of two months of therapy. On the  contrary, beta blockers, calcium channel blockers, isosorbide dinitrate and diuretics, etc.,  which the patients were taking for hypertension and angina control, could not be withdrawn  completely (Table XIV) but their doses substantially reduced to half of the quantity which  they were taking. Similarly the hypertensive patients did not show any significant change in  their blood pressure levels. Total number of patients who did not respond to treatment were  525 (348 ischaemic and 177 diabetics out of 5000 patients).

Aloe Vera Australia Products. Please click here… Aloe Vera Australia

 

Discussion  

In the present study it has been noticed that the plant had a definite role in the prevention  and management of atherosclerotic heart disease. The plant also had a definite role in  controlling the blood sugar level in diabetic patients. The exact mechanism of the plant Aloe  vera and Husk of Isabgol is not known but it appears that both these substances act by their  high fibre contents and these substances need further evaluation. In the entire study no  untoward side effect was noticed and all the patients were followed for a period of five years  from July 1978 to June 1983 and all the patients turned up for regular follow up and till date  all the 5000 patients are surviving. The diabetic patients, except 177 patients, are on diet  control alone and none of them has ever complained about any hypoglycemic episode  during the study. There is no such study available in medical literature where such a large  number (5000 patients) of patients are being followed up for five years and no Indian plant  has ever been tried with such success. So this is a unique study of its own type.

To conclude, the Indian plant Aloe vera, when mixed with the Husk of Isabgol, was given  to the patients of atherosclerotic heart disease, there was a definite and substantial  improvement (about 95%) in their clinical profile apart from biochemical changes and ECG  tracings. These two substances need further evaluation to find out the exact mechanism of  action on atherosclerosis.

Aloe Vera Australia Products. Please click here… Aloe Vera Australia

 

REFERENCES
  1. https://www.scientificamerican.com/article/what-are-the-benefits-of-drinking-aloe-juice/
  2. https://www.cdc.gov/chronicdisease/resources/publications/factsheets/physical-activity.htm#:~:text=Not%20getting%20enough%20physical%20activity%20can%20lead%20to%20heart%20disease,cholesterol%2C%20and%20type%202%20diabetes.
  3. https://www.indiatoday.in/lifestyle/wellness/story/aloe-vera-juice-5-amazing-benefits-of-guzzling-the-humble-health-drink-316590-2016-04-063
  4. https://www.news18.com/news/lifestyle/aloe-vera-may-have-beneficial-effects-for-diabetics-1264443.html
  5. https://www.womansworld.com/posts/health/lower-blood-pressure-numbers-137544